It is a 611 kilometer (379 miles) distance between Cappadocia and Pamukkale, a drive of 9 hours. There are no direct flights or trains between Cappadocia and Pamukkale, so you’ll have to go by bus or car.
Bus companies don’t take you directly to Pamukkale, but to the Denizli otogar bus station. There are busses operating every day from Nevşehir (Cappadocia) to Denizli. You may find a direct bus all the way from Nevşehir (Cappadocia) to Denizli (Pamukkale) or vice-versa, but it’s also possible you’ll have to change busses in Konya. This is not a big problem, but it adds some travel time to your trip. If you plan to spend a night in Konya or Pamukkale along the way, you can use direct buses for both segments of your journey (that is, directly from Pamukkale to Konya, and Konya to Cappadocia).
The bus drive from Nevşehir (Cappadocia) to Denizli otogar bus station will take about 9 hours.
The bus will drop you at Denizli otogar bus station and then you have to get on the minibus (Turkish: Dolmus) to Pamukkale. This is about 18 kilometers / 11 miles away. The minibuses depart the Otogar’s Platform (Gate) 76 on the lower level (below the intercity bus gates) every 15 to 20 minutes. For the minibus from Denizli otogar to Pamukkale the price will be 5 Turkish Lira (1,30 euros or $2).
It’s a 611 kilometer (379 miles) distance between Cappadocia and Pamukkale. By car this will take a drive of 9 hours.